Cyclic AMP Imaging Sheds Light on PDF Signaling in Circadian Clock Neurons
نویسندگان
چکیده
In Drosophila, the neuropeptide PDF is required for circadian rhythmicity, but it is unclear where PDF acts. In this issue of Neuron, Shafer et al. use a novel bioimaging methodology to demonstrate that PDF elevates cAMP in nearly all clock neurons. Thus, PDF apparently exerts more widespread effects on the circadian clock network than suggested by previous studies of PDF receptor expression.
منابع مشابه
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ورودعنوان ژورنال:
- Neuron
دوره 58 شماره
صفحات -
تاریخ انتشار 2008